Full disclosure:  I did not have high hopes for this interview.  Hillary might be a worse actress than she is a politician.. I know, it seems impossible, but it might be true.  Since Clinton refuses to answer real questions by avoiding press conferences, every interview seems to be peppered with softballs of questions.  This one was not.  Clearly comedy, but still great.  
The Funny Or Die skit, “Between Two Ferns” is usually pretty solid.  Zach Galifianakis makes it a point to ask people politically incorrect and extremely awkward questions that they would normally refuse to answer.  Zach takes a couple shots at Trump, which can be expected in any Hillary interview, but for the most part, makes fun of Hillary and Obama.